On the Clock: Decoding Circadian Skincare
Why tapping into your body’s internal clock could change your beauty game for good.
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On the Clock: Decoding Circadian Skincare
Why tapping into your body’s internal clock could change your beauty game for good.
With it’s whirlwind innovations, research breakthroughs and rapid ingredient explorations: the avant-garde of skincare is becoming ever more futuristic. But, one emerging sector is taking a different focus, stripping away the glossy fads and investigating ways to work with the skin, rather than seeking to change it. In this field, skin innovators are tapping into natural processes in the pursuit of healthier skin.
While most of beauty browsers will be familiar with day creams, night creams and AM vs. PM routines, and the more detail minded may fastidiously reserve their acids and retinoids for evening application, we don’t always pause to consider why. This is where the concept of circadian skincare comes into play: strategically using certain ingredients in the morning or the evening to help support and enhance what your skin is already naturally doing.
It’s a field that sits alongside the emerging trend for supercharging your sleep. Ingredients such as lavender and magnesium appearing in balms and butters designed to help you settle down for a good night’s rest, which in turn supports your body’s as it repairs and restores. Be it Verden’s Nocturn range, backed with softly scented ingredients designed to induce slumber, Neom’s pillow mists, or Neuraé’s soothing sleep mask: night-time is golden.
Perhaps it was inevitable, then, that the next step in skincare would be to target your routines to what’s happening around the clock: making the most of your newly improved Zzzzs.
If it’s all sounding a bit complicated, the good news is that it’s simpler than the science makes it sound, and the even better news is that we’ve called on an expert to help break the concept down into something you can easily add into your own routine.
Katey Mandy founded botanical based, science backed skincare brand RAESO based precisely on the idea that skincare could, and should, be used alongside your skin’s natural processes. Here, she sits down with Liberty to share everything you need to know about the wonderful world of biohacking your skin’s circadian rhythms.
Circadian Skincare: Decoded
Can you briefly explain the concept of circadian skincare?
Circadian skincare is built on a simple but powerful truth: your skin is not static. It follows a 24-hour biological rhythm, just like the rest of your body. Circadian skincare is built around the understanding that skin has distinct 24-hour needs: it behaves differently at 8am than it does at midnight. During the day, it prioritises defence: neutralising oxidative stress, reinforcing the barrier and protecting against UV and pollution. At night, it shifts into repair mode, increasing cellular turnover, DNA repair activity and regeneration.
True circadian formulation goes beyond simply labelling products “day” and “night.” It requires time-release delivery systems that mirror these biological windows - releasing antioxidants when skin is under environmental attack, and gradually delivering renewal actives overnight when permeability and repair pathways peak. It’s about precision timing, and supporting the skin continuously across the full 24-hour cycle.
Efficacy isn’t just about what you use, but when and how it’s delivered.
THE MORNING ROUTINE
RAESO
Morning Dew Vitamin C Serum 30ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Skin Rocks
The Cleansing Balm 100ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
RAESO
Sun Milk Drops Tinted SPF50 45ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Augustinus Bader
The Vitamin C Serum 30ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
RAESO
Tranquillity Water Activating Mist 100ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
DARLING
Screen-Me SPF50 150ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
How and when did you first find out about circadian skincare?
When I was developing RAESO, I wasn’t interested in adding more products into an already saturated market. I wanted to understand exactly when the skin is most receptive, when it’s under the greatest stress, and when its regenerative processes are at their peak across the 24-hour cycle. That became the lens through which every formula was created.
As the science around chronobiology continues to evolve and we understand more about the biology of our skin, it’s becoming clear that timing is a critical factor in how well skincare performs. Efficacy isn’t just about what you use, but when and how it’s delivered.
Our collaboration with Dr. Daniel B. Yarosh, a pioneer in DNA repair research (and ex Head of Estee Lauder research), brought further depth and rigour to that philosophy. Working alongside him grounded our approach in measurable biological processes - particularly nuclear DNA repair pathways and time-dependent, encapsulated delivery systems. It affirmed that real, visible change happens when formulations are aligned with the skin’s internal clock, not simply layered onto the surface.
Personally, it simplified everything. I stopped over-layering and started being intentional. In the morning, I focus on antioxidant defence and protection. At night, I focus on repair and cellular renewal. More broadly, it shifts skincare from being reactive, and treating problems as they arise, to being proactive and preventative. You’re supporting skin before damage accumulates.
KATEY MANDY'S CIRCADIAN ROUTINE
RAESO founder Katet Mandy
MORNING
“A gentle cleanse, an antioxidant serum (such as a stabilised vitamin C), a barrier-supporting moisturiser, and broad-spectrum SPF. This is your defence ritual.”
EVENING
“Cleanse thoroughly to remove the day, apply a retinal, peptide or renewal serum, and seal with a ceramide-rich cream. This is your repair ritual.”
What are some of the processes that happen in the skin that we can tap into?
Overnight is when the magic happens. Skin permeability increases, cellular turnover accelerates, and DNA repair activity peaks. Blood flow to the skin rises, and transepidermal water loss also increases, which is why skin can feel drier by morning. This is the ideal window for ingredients like retinal, peptides, DNA repair enzymes, and barrier-supporting lipids - actives that stimulate renewal while reinforcing resilience.
In the morning, antioxidants are key. Vitamin C is foundational because it helps neutralise free radicals generated by UV exposure and pollution, supporting the skin’s defence systems when oxidative stress is at its highest. Niacinamide works beautifully during the day for barrier reinforcement, tone regulation and reducing inflammation, while lightweight peptides can help strengthen skin resilience without overloading it. SPF, of course, is non-negotiable - it’s the final shield in your daytime defence strategy.
When you apply ingredients at the moment skin is biologically primed to use them, you get better results with less irritation.
How did the idea of circadian skincare impact the way you created products?
Completely. At RAESO, we formulate according to the time-of-day function. Our daytime formulas prioritise antioxidant networks and environmental resilience. Our nighttime formulas focus on renewal, DNA repair support and barrier restoration.
It affects texture, delivery systems, ingredient buffering, even pH considerations. For example, our retinal serum is encapsulated and paired with soothing New Zealand botanicals to align with overnight regeneration without overwhelming the skin. Every formula begins with the question: what is skin trying to do at this hour?
THE EVENING ROUTINE
RAESO
Cocoon Ceramide Cream 50ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
VERDEN
Nocturne Sleep Mist 60ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
RAESO
Golden Nectar Manuka Honey Enzyme Cleanser 150ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Augustinus Bader
The Retinol Serum 15ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
NEURAÉ
Harmony The Sleeping Mask 60ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
VERDEN
Nocturne Bath Salts 500g
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
VERDEN
Nocturne Night Balm 75ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
111SKIN
Black Diamond Retinol Oil 30ml
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
Free UK Standard Delivery on all orders over £100! Delivered within 3-5 working days. Normally £5.95.
What are the top three things you would want people to know about circadian skin science?
Firstly, your skin is already very good at its job. It is constantly adjusting, responding, repairing and defending, quietly and continuously, across a 24-hour cycle. Its priorities shift throughout the day. The goal isn’t to override that intelligence, but to respect it.
Secondly, timing matters as much as ingredients. The same product used at the wrong time may not deliver the same results. Timing influences how well your skin absorbs and responds to ingredients
Thirdly, when you support what the skin is already trying to do - pairing the right ingredients with its changing needs - you allow it to work better, not harder. Skin responds more effectively at certain points in the day. When skincare is in sync with that rhythm, results are optimised. Put simply, when you factor time into your routine, you maximise the power of your skincare. And often, everything becomes simpler, and more effective.
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